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KMID : 0363220080460101398
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Korean Journal of Dermatology
2008 Volume.46 No. 10 p.1398 ~ p.1401
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A Case of Lymphangioma Treated by OK-432 (Picibanil(R)) Sclerotherapy
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Kim Bo-Suk
Park Seok-Don
Won Tai-Hyok
Seo Phil-Seung
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Abstract
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Lymphangioma is an uncommon, benign hyperproliferation of the lymphatic vessels, and this consists of dilated
lymphatic channels lined by a normal, single layer of endothelial cells. Various methods have been tried for the
treatment of lymphangioma, including cryotherapy, electrocauterization, surgical excision, laser therapy, radiotherapy
and itralesional injection of sclerosing agents. Yet these methods have shown low success rates and various side
effects. It has recently been reported that intralesional injection of OK-432 is a safe and effective alternative therapy
for lymphangioma, and especially for macrocystic lesion. In this report, we describe a patient with lymphangioma on
the upper labial mucosa and this patient was successfully treated with intralesional injection of OK-432 without any
serious complications. To the best of our knowledge, this is the first such case reported on in the Korean
dermatological literature.
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KEYWORD
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Lymphangioma ark, OK-432
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